Publications
Engineering a Highly Regioselective Fungal Peroxygenase for the Synthesis of Hydroxy Fatty Acids
P Gomez de Santos, C
Aranda, A Fernandez-Garcia, A But, P Molina-Espeja, D Mate Maté,
D Gonzalez-Perez, W Zhang, J Kiebist, K Scheibner, M Hofrichter, J
Sanz-Aparicio, F Hollmann, A Gutiérrez, and M Alcalde
Angewandte Chemie (2023) 62, e202217372 (doi: 10.1002/anie.202217372)
The mobility of the cap
domain is essential for the substrate promiscuity of a family IV
esterase from sorghum rhizosphere microbiome
M Distaso, I Cea-Rama, C Coscolín, T N. Chernikova, H Tran, M Ferrer, J Sanz-Aparicio, PN Golyshin
Applied and Environmental Microbiology Journal (2023) 89 (1), e01807-22 (doi: 10.1128/aem.01807-22)
Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor
L Fernandez-Lopez, I
Cea-Rama, J Alvarez-Malmagro, AK Ressmann, JL Gonzalez-Alfonso, C
Coscolín, P Shahgaldian, FJ Plou, JModregger, M Pita, J
Sanz-Aparicio, M Ferrer
ChemComm (2023) 59 (62), 9469-9472 (doi: 10.1039/D3CC01946B)
Increased thermostability of an engineered flavin-containing
monooxygenase to remediate trimethylamine in fish protein hydrolysates
M Goris, I Cea-Rama, P Puntervoll, R Ree, D Almendral, J Sanz-Aparicio, M Ferrer, GE Kjæreng Bjerga
Applied and Environmental Microbiology Journal (2023) 89 (6), e00390-23 (doi: 10.1128/aem.00390-23)
Relevance of aromatic and polar amino acids in the specificity of
Inulinase ISO3 from Kluyveromyces marxianus: A molecular dynamics
approach with an experimental verification
J Trapala, M González-Andrade, C Olvera, M Cayetano, J Sanz-Aparicio, E Jimenez-Ortega, I Bustos-Jaimes, C Montiel
International Journal of Biological Macromolecules (2023) 243, 124734 (doi: 10.1016/j.ijbiomac.2023.124734)
Enzymes for consumer products to achieve climate neutrality
Patricia Molina-Espeja, Julia Sanz-Aparicio, Peter N Golyshin, Ana
Robles-Martín, Víctor Guallar, Fabrizio Beltrametti,
Markus Müller, Mikhail Yakimov, Jan Modregger, Moniec van Logchem,
Philippe Corvini, Patrick Shahgaldian, Christian Degering, Susanne
Wieland, Anne Timm, Carla C C R de Carvalho, Ilaria Re, Sara Daniotti,
Stephan Thies, Karl-Erich Jaeger, Jennifer Chow, Wolfgang R Streit,
Roland Lottenbach, Rainer Rösch, Nazanin Ansari, Manuel Ferrer,
The FuturEnzyme Consortium
Oxford Open Climate Change (2023) kgad003, (doi: 10.1093/oxfclm/kgad003)
Insights into the Structure of the Highly Glycosylated Ffase from Rhodotorula dairenensis Enhance Its Biotechnological Potential
E.
Jiménez-Ortega, E. Narmontaite, B. González-Pérez,
Francisco J. Plou, M Fernández-Lobato, J Sanz-Aparicio
International Journal of Molecular Sciences (2022) 23, 14981 (doi: 10.3390/ijms232314981)
Structure–function insights
into the fungal endo-chitinase Chit33 depict its mechanism on chitinous
material
E Jiménez-Ortega, PE Kidibule, M
Fernández-Lobato, J Sanz-Aparicio
International Journal of Molecular Sciences (2022) 23, 7599
(doi:
https://doi.org/10.3390/ijms23147599)
Crystal structure of a family VIII β-lactamase fold hydrolase
reveals the molecular mechanism for its broad substrate scope
I Cea-Rama, C Coscolín, J L Gonzalez-Alfonso, J Raj, M
Vasiljević, F J Plou, M Ferrer, J Sanz-Aparicio
The Febs Journal (2022) (doi: https://doi.org/10.1111/febs.16554)
The bone-degrading enzyme machinery: from multi-component understanding
to the treatment of residues from the meat industry
L
Fernandez-Lopez, S Sanchez-Carrillo, A García-Moyano, E
Borchert, D
Almendral, S Alonso, I Cea-Rama, N Miguez, Ø Larsen, J
Wernere, KS
Makarova, FJ Plou, TG Dahlgren, J Sanz-Aparicio, U. Hentschelc, G E
Kjæreng and M Ferrer
Computational
and Structural Biotechnology Journal (2021) 19,
6328-6342 (doi: 10.1016/j.csbj.2021.11.027)
Structural
inspection and protein motions modelling of a fungal glycoside
hydrolase family 18 chitinase by crystallography depicts dynamic
enzymatic mechanism
E Jiménez-Ortega, PE Kidibule, M
Fernández-Lobato, J Sanz-Aparicio
Computational
and Structural Biotechnology Journal (2021) 19,
5466-5478 (doi:
10.1016/j.csbj.2021.09.027)
Enzymatic
Synthesis of Phloretin α‐Glucosides Using a Sucrose
Phosphorylase
Mutant and its Effect on Solubility, Antioxidant Properties and Skin
Absorption
J L Gonzalez‐Alfonso, Z Ubiparip, E Jimenez‐Ortega, A
Poveda, C Alonso, L Coderch, J Jimenez‐Barbero, J Sanz‐Aparicio, A O
Ballesteros, T Desmet, F J Plou
Advanced Synthesis &
Catalysis (2021) 363, 3079-3089 (doi:
10.1002/adsc.202100201)
Multiple
substrate recognition by yeast diadenosine and diphosphoinositol
polyphosphate phosphohydrolase through phosphate clamping
María
Ángeles Márquez-Moñino, Raquel
Ortega-García, Megan L. Shipton, Elsa
Franco-Echevarría, Andrew M. Riley, Julia Sanz-Aparicio,
Barry V.L.
Potter and Beatriz González
Science Advances (2021)
7, abf6744 (doi:
10.1126/sciadv.abf6744)
Phylogenetic,
functional and structural characterization of a GH10 xylanase active at
extreme conditions of temperature and alkalinity
D Talens-Perales, E Jiménez-Ortega, P
Sánchez-Torres, J Sanz-Aparicio, J Polaina
Computational
and Structural Biotechnology Journal (2021) 19, 2676-2686
(doi:
10.1016/j.csbj.2021.05.004)
New insights into the molecular mechanism behind mannitol and
erythritol fructosylation by β-fructofuranosidase from Schwanniomyces occidentalis
D Rodrigo-Frutos, M Ramirez-Escudero, D Piedrabuena, E
Jiménez-Ortega, N Miguez, FJ Plou, J Sanz-Aparicio, M
Fernández-Lobato
Scientific
Reports (2021) 11, article number 7158 (doi: 10.1038/s41598-021-86568-6)
Structure
and evolutionary trace-assisted screening of a residue swapping the
substrate ambiguity and chiral specificity in an esterase
I Cea-Rama, C Coscolín, P Katsonis, R Bargiela, N Golyshin,
O Lichtarge, M Ferrer, J Sanz-Aparicio
Computational
and Structural Biotechnology Journal (2021) 19, 2307-2317
(doi: 10.1016/j.csbj.2021.04.041)
Genetically
engineered proteins with two active sites for enhanced biocatalysis and
synergistic chemo- and biocatalysis.
S Alonso, G Santiago, I Cea-Rama, L
Fernández-López,
Coscolín, J Modregger, AK Ressmann, M
Martínez-Martínez, H Marrero, R Bargiela, M Pita,
JL
Gonzalez-Alfonso, ML Briand, D Rojo, C Barbas, FJ Plou, P N. Golyshin,
P Shahgaldian, J Sanz-Aparicio, V Guallar, and M Ferrer
Nature
Catalysis (2020) 3, 319–328 (doi:10.1038/s41929-019-0394-4)
Tuning the Properties of Natural Promiscuous Enzymes by Engineering
Their Nanoenvironment
Carolina
I. Giunta, Isabel Cea-Rama, Sandra Alonso, Manon L. Briand, Rafael
Bargiela, Cristina Coscolín, Philippe F.-X. Corvini, Manuel
Ferrer,
Julia Sanz-Aparicio, and Patrick Shahgaldian
ACS
Nano (2020) 14, 17652–17664
(doi: 10.1021/acsnano.0c08716)
Structural analysis of the reducing-end xylose-releasing
exo-oligoxylanase Rex8A from Paenibacillus
barcinonensis BP-23 deciphers its molecular specificity
E Jiménez-Ortega, S Valenzuela, M
Ramírez-Escudero, FJ Pastor and J Sanz-Aparicio
The Febs Journal (2020)
287, 5362–5374
(doi: 10.1111/febs.15332)
The
cryo-EM structure of Thermotoga
maritima β-galactosidase: quaternary structure
guides protein engineering.
Míguez-Amil S, Jiménez-Ortega E,
Ramírez-Escudero
M, Talens-Perales D, Marín-Navarro J, Polaina J,
Sanz-Aparicio
J, Fernández-Leiro R
ACS
Chemical Biology (2020) 15, 179-188 (doi:10.1021/acschembio.9b00752)
Deciphering
the molecular specificity of phenolic compounds as inhibitors or
glycosyl acceptors of β-fructofuranosidase from Xanthophyllomyces dendrorhous
Mercedes Ramirez-Escudero, Noa Miguez, Maria Gimeno-Perez, Antonio O.
Ballesteros, Maria Fernandez-Lobato, Francisco J. Plou and
Julia
Sanz-Aparicio
Scientific
Reports (2019) 9:17441 (doi:10.1038/s41598-019-53948-y)
Structural basis of the inhibition of GH1 β-glucosidases by
multivalent pyrrolidine iminosugars
M
Martínez-Bailén, E Jiménez-Ortega, AT
Carmona, I Robina, J
Sanz-Aparicio, D Talens-Perales, J Polaina, C Matassini, F Cardona and
A J Moreno-Vargas
Bioorganic
Chemistry (2019) 89, 103026-103036 (doi:10.1016/j.bioorg.2019.103026)
Yeast
cultures expressing the Ffase from Schwanniomyces
occidentalis,
a simple system to produce the potential prebiotic sugar 6-kestose
D. Rodrigo-Frutos, D. Piedrabuena, J. Sanz-Aparicio, M.
Fernández-Lobato
Applied Microbiology and
Biotechnology (2018) 103, 279–289
(doi:10.1007/s00253-018-9446-y)
Structural
Insights into the Substrate Promiscuity of a Laboratory-Evolved
Peroxygenase
Mercedes
Ramirez-Escudero, Patricia Molina-Espeja, Patricia Gomez de Santos,
Martin Hofrichter, Julia Sanz-Aparicio and Miguel Alcalde
ACS
Chemical Biology (2018) 13, 3259–3268 (doi:10.1021/acschembio.8b00500)
Fructosylation of hydroxytyrosol by the
β-fructofuranosidase from Xanthophyllomyces dendrorhous:
Insights into
the molecular basis of the enzyme specificity
Miguez M,
Ramírez-Escudero M, Gimeno-Pérez M, Poveda A,
Jiménez-Barbero J,
Ballesteros AO, Fernández-Lobato M, Sanz-Aparicio J, and
Plou FJ
ChemCatChem (2018) 10,
4878–4887 (doi:10.1002/cctc.201801171)
Use of chitin and chitosan to produce new
chitooligosaccharides by chitinase Chit42: enzymatic activity and
structural basis of protein specificity
PE Kidibule, P Santos
Moriano, E Jiménez Ortega, M Ramírez Escudero, MC
Limón, M Remacha, FJ
Plou, J Sanz Aparicio and M Fernández Lobato
Microbial Cell Factories (2018)
17:47 (doi:10.1186/s12934-018-0895-x)
The
crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate
2-kinase reveals a new zinc-binding site and key features for protein
function
Franco-Echevarría E, Sanz-Aparicio J, Brearley CA,
González-Rubio JM, González B.
Journal of Biological Chemistry (2017) 292, 10534-10548
(doi:10.1074/jbc.M117.780395)
Structural features of Aspergillus
niger β-galactosidase define its activity against
glycoside linkages
Rico-Díaz, A., Ramírez-Escudero, M.,
Vizoso-Vázquez, A., Cerdán, M.E., Becerra, M. and
Sanz-Aparicio, J.
The
FEBS Journal (2017) 284, 1815–1829 (doi:10.1111/febs.14083)
Structural
and functional characterization of a ruminal β-glycosidase
defines a novel subfamily of glycosyl hydrolase family 3 with permuted
domain topology
Mercedes Ramírez-Escudero, Mercedes V. del Pozo, Julia
Marín-Navarro, Beatriz González, Peter N.
Golyshin, Julio Polaina, Manuel Ferrer and Julia Sanz-Aparicio
Journal of
Biological Chemistry (2016) 291,
24200-24214
(doi:10.1074/jbc.M116.747527)
The glycoside hydrolase family
8 reducing-end xylose-releasing exo-oligoxylanase Rex8a from Paenibacillus barcinonensis
BP-23 is active on branched xylooligosaccharides
Susana Valenzuela, Sergi
López, S., Peter Biely, Julia Sanz-Aparicio, F. Javier Pastor
Applied
and Environmental Microbiology (2016) 82, 5116-5124 (doi:10.1128/AEM.01329-16)
Molecular
characterization and heterologous expression of a Xanthophyllomyces
dendrorhous α-glucosidase with potential for
prebiotics production
Patricia
Gutiérrez-Alonso, María Gimeno-Pérez,
Mercedes
Ramírez-Escudero, Francisco J. Plou, Julia Sanz-Aparicio,
María Fernández-Lobato
Applied
Microbiology and Biotechnology (2016) 100, 3125-3135
(doi: 10.1007/s00253-015-7171-3)
Structural analysis of β-fructofuranosidase from Xanthophyllomyces dendrorhous
reveals unique features and the crucial role of N-glycosylation in
oligomerization and activity
M Ramírez-Escudero, M Gimeno-Pérez, B
González, D
Linde, Z Merzdo, M Fernández-Lobato, J Sanz-Aparicio
Journal of
Biological Chemistry (2016) 291,
6843-6857 (doi:10.1074/jbc.M115.708495)
Molecular
characterization and heterologous expression of a Xanthophyllomyces
dendrorhous α-glucosidase with potential for
prebiotics production
Patricia
Gutiérrez-Alonso, María Gimeno-Pérez,
Mercedes
Ramírez-Escudero,Francisco J. Plou, Julia Sanz-Aparicio,
María
Fernández-Lobato
Applied
Microbiology and Biotechnology (2015) 100, 3125-3135
(doi:
10.1007/s00253-015-7171-3)
The legacy of women to
crystallography
Sanz-Aparicio,
J.
in Celebrating
100 years of modern crystallography. (Mancheño,
J.M., coord.), Arbor (2015) 191 (772): a223 [PDF-copy]
Exploring
multimodularity in plant cell wall deconstruction: structural and
functional analysis of Xyn10C containing the CBM22-1-CBM22-2 tandem
M. Angela Sainz-Polo, Beatriz González, Margarita
Menéndez, F.I. Javier Pastor and Julia Sanz-Aparicio
Journal
of Biological Chemistry (2015) 290, 17116-17130 (doi:10.1074/jbc.M115.659300)
A new calmodulin binding motif for inositol 1,4,5-trisphosphate
3-kinase regulation
Franco-Echevarria, E., Baños-Sanz, J.I., Monterroso, B.,
Round A, Sanz-Aparicio, J., González, B.
Biochemical
Journal (2014) 463, 319-328 (doi:10.1042/BJ20140757)
Structural
analysis of glucuronoxylan specific Xyn30D and its attached CBM35
domain give insights into the role of modularity in specificity
Sainz-Polo, M.A.Valenzuela, S., González-Pérez,
B., Pastor, F.J., Sanz-Aparicio, J.
Journal
of Biological Chemistry (2014) 289, 31088-31101
(doi:
10.1074/jbc.M114.597732)
Crystallization and preliminary
X-ray diffraction data of β-galactosidase from Aspergillus niger
Rico-Díaz, A., Vizoso-Vázquez,
A-, Cerdán, M.A., Becerra, M., Sanz-Aparicio, J.
Acta Crystallographica (2014)
F70, 1529-1531 (doi:10.1107/S2053230X14019815)
Crystallization and preliminary X-ray diffraction analysis
of Xyn30D from Paenibacillus
barcinonensis
Sainz-Polo, M.A.Valenzuela, S., Pastor, F.J.,
Sanz-Aparicio, J.
Acta
Crystallographica (2014) 963-966 (doi:10.1107/S2053230X14012035)
El
arma secreta de la biotecnología
Julia Sanz Aparicio
in A
través del cristal. Cómo la
cristalografía ha cambiado la visión del mundo
(2014). (M.
Martínez-Ripoll, J.A. Hermoso y Armando Albert, coord.), CSIC-Catarata, pp.
155-170, ISBN:
978-84-00-09800-1.
Crystal structure and functional insights into uracil-DNA glycosylase
inhibition by phage ϕ29 DNA mimic protein p56
José
Ignacio Baños-Sanz, Laura Mojardín, Julia
Sanz-Aparicio, José M.
Lázaro, Laurentino Villar, Gemma Serrano-Heras, Beatriz
González, and
Margarita Salas
Nucleic
Acids Research (2013) 41, 6761-6773 (doi:10.1093/nar/gkt395)
Synthesis
of 6-Kestose using an Efficient β-Fructofuranosidase
Engineered by Directed Evolution
Miguel de Abreu, Miguel Alvaro-Benito, Julia Sanz-Aparicio, Francisco
J. Plou, Maria Fernandez-Lobato and Miguel Alcalde
Advanced
Synthesis & Catalysis (2013) 355, 1698–1702 (doi:10.1002/adsc.201200769)
The three-dimensional structure of Saccharomyces
invertase: role of a noncatalytic domain in oligomerization and
substrate specificity
M. Angela Sainz-Polo, Mercedes Ramírez-Escudero, Alvaro
Lafraya, Beatriz González, Julia Marín-Navarro,
Julio Polaina and Julia Sanz-Aparicio
Journal
of Biological Chemistry (2013) 288, 9755-9766 (doi:10.1074/jbc.M112.446435)
NADP+ Binding to the Regulatory Subunit of
Methionine Adenosyltransferase II Increases Intersubunit Binding
Affinity in the Hetero-Trimer
Gonzalez,
B; Garrido, F; Ortega, R; Martínez-Julvez, M;
Revilla-Guarinos, A;
Pérez-Pertejos. Y; Velázquez-Campoy, A;
Sanz-Aparicio, J; and Pajares, M
PLoS
ONE (2012) 7(11), e50329 (doi:10.1371/journal.pone.0050329)
Conformational
Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon
Substrate Binding: The Role of N-lobe and Enantiomeric Substrate
Preference
José Ignacio Baños-Sanz, Julia Sanz-Aparicio,
Hayley
Whitfield, Chris Hamilton, Charles A. Brearley and Beatriz
González
Journal
of Biological Chemistry (2012) 287, 29237-29249 (doi:10.1074/jbc.M112.363671)
Crystallization and
preliminary X-ray diffraction analysis of the invertase from Saccharomyces cerevisiae
M. A. Sainz-Polo, A. Lafraya, A. Polo, J.
Marín-Navarro, J. Polaina and J. Sanz-Aparicio
Acta
Crystallographica (2012) F68, 1538-1541 (doi:10.1107/S1744309112044417)
Expression,
purification, crystallization and
preliminary X-ray diffraction analysis of the apo form of InsP(5) 2-K
from Arabidopsis thaliana
J.I. Baños-Sanz, J. Sanz-Aparicio, C.A.
Brearley and B. González
Acta
Crystallographica (2012) F68, 701-704 (doi:10.1107/S1744309112017307)
Structural and kinetic insights reveal that the amino acid pair
GLN228/ASN254 modulates the transfructosylating specificity of Schwanniomyces occidentalis
β-fructofuranosidase, an enzyme that produces prebiotics
Miguel
Alvaro-Benito, M. Angela Sainz-Polo, David Gonzalez-Perez, Beatriz
Gonzalez, Francisco J. Plou, Maria Fernandez-Lobato, and Julia Sanz
Aparicio
Journal
of Biological Chemistry (2012) 287, 19674-19686 (doi:10.1074/jbc.M112.355503)
An analysis of subdomain orientation, conformational change and
disorder in relation to crystal packing of aspartic proteinases
D. Bailey, E.P. Carpenter, A. Coker, S. Coker, J. Read, A.T. Jones, P.
Erskine, C.F. Aguilar, M. Badasso, L. Toldo, F. Rippmann, J.
Sanz-Aparicio, A. Albert, T.L. Blundell, N.B., Roberts, S.P. Wood and
J.B. Cooper
Acta
Crystallographica (2012) D68, 541-552 (doi:
10.1107/S0907444912004817)
Structural
basis of specificity in tetrameric Kluyveromyces
lactis β-galactosidase
Pereira-Rodríguez, A; Fernández-Leiro,
R; González-Siso, MI; Esperanza
Cerdán,
M; Becerra, M; Sanz-Aparicio, J
Journal
of Structural Biology (2012) 177, 392–401 (doi:10.1016/j.jsb.2011.11.031)
Nobel
de Química 2011 a Daniel Shechtman por su descubrimiento de
los cuasicristales y de una simetría "imposible"
Julia Sanz-Aparicio
mi+d
(2011) published in Análisis
Madri+d on 15 Nov. 2011 [PDF-copy]
Fructo-oligosaccharide
synthesis by mutant versions of Saccharomyces
cerevisiae invertase
Lafraya, A., Sanz-Aparicio, J., Polaina, J. and
Marín-Navarro, J.
Applied
Environmental Microbiology (2011)
77, 6148-6157 (doi:10.1128/AEM.05032-11)
New
insights
into the fructosyltransferase
activity of Schwanniomyces
occidentalis β-fructofuranosidase,
emerging
from nonconventional codon usage and directed mutation
Alvaro-Benito, M., Abreu,
M., Portillo, F., Sanz-Aparicio, J. and Fernández-Lobato, M.
Appl.
Environ. Microbio. (2010) 7491-7499 (doi:10.1128/AEM.01614-10)
Crystallization and
preliminary X-ray diffraction analysis of the fructofuranosidase from
Xanthophyllomyces
dendrorhous
Polo, A., Linde, D.,
Estévez, M., Fernández-Lobato, M. and
Sanz-Aparicio, J.
Acta
Cryst. (2010) F66, 1441-1444 (doi:10.1107/S1744309110029192)
Structural analysis of Saccharomyces
cerevisiae
α-galactosidase and its complexes with natural substrates
reveals
new insights into substrate specificity of GH27 glycosidases
Rafael Fernández-Leiro, Ángel
Pereira-Rodríguez,
M. Esperanza Cerdán, Manuel Becerra and Juliana Sanz-Aparicio
Journal
of Biological Chemistry (2010) 285, 28020-28033 (doi:10.1074/jbc.M110.144584)
Inositol
1,3,4,5,6-pentakisphosphate 2-kinase
is a distant IPK member with a singular inositide binding site for
axial 2-OH recognition
B. González, J.
Baños-Sanz, M. Villate, C. Brearley and J. Sanz-Aparicio
Proceedings
of the National Academy of Sciences (2010) 107,
9608-9613 (doi:10.1073/pnas.0912979107)
Structural
and kinetic analysis of
Schwanniomyces
occidentalis invertase reveals a new oligomerization
pattern and the role of its supplementary domain in substrate binding
Alvaro-Benito, M., Polo, A.,
González, B., Fernández-Lobato, M. and
Sanz-Aparicio, J.
Journal of Biological
Chemistry (2010) 285,
13930-13941 (doi:10.1074/jbc.M109.095430)
Crystallization
and preliminary X-ray crystallographic analysis of
β-galactosidase from
Kluyveromyces lactis
Pereira-Rodríguez,
A. Fernández-Leiro, R., González-Siso, M.,
Cerdán, E., Becerra, M. and Sanz-Aparicio, J.
Acta
Crystallographica (2010) F66, 297-300 (doi:10.1107/S1744309109054931)
Crystallization
and preliminary X-ray
diffraction analysis of inositol 1,3,4,5,6-pentakisphosphate kinase
from Arabidopsis
thaliana
Baños-Sanz, J.I., Villate, M., Sanz-Aparicio, J., Brearley,
C.A. and González B.
Acta
Crystallographica (2010) F66, 102-106 (doi:10.1107/S1744309109051057)
Crystallization
and preliminary X-ray diffraction analysis of α-galactosidase
from Saccharomyces
cerevisiae
Fernández-Leiro,
F., Pereira, A., Cedán, E. Becerra-Fernández, M.
and Sanz-Aparicio, J.
Acta
Crystallographica (2010) F66, 44-47 (doi:10.1107/S1744309109047794)
Structural insights into the specificity of Xyn10B
from Paenibacillus
barcinonensis and its improved stability by
forced protein evolution
Gallardo, O. Pastor, F.J., Polaina, J., Díaz, P., Vogel, P.
Isorna, P., González-Pérez, B. and Sanz-Aparicio,
J.
Journal
of Biological Chemistry (2010) 285, 2721-2733 (doi:10.1074/jbc.M109.064394)
Crystallization
and preliminary X-ray diffraction analysis of the fructofuranosidase
from Schwanniomyces
occidentalis
Polo-Rivas, A.
Alvaro-Benito, A., Fernández-Lobato, M. and Sanz-Aparicio, J.
Acta
Crystallographica (2009) F65, 1162-1165 (doi:10.1107/S174430910903938)
Crystal
structures of Paenibacillus
polymyxa β-glucosidase B
complexes
reveal the molecular basis of substrate specificity and give insights
into the catalytic mechanism of family I glycosidases
Isorna, P., Polaina, J.,
Latorre-García. L., Cañada, F.J.,
González, B. y Sanz-Aparicio, J.
Journal of Molecular Biology (2007) 371,
1204-1218
Xylanases: Molecular
properties and applications
Pastor, F.J., Gallardo, O.,
Sanz-Aparicio, J. y Díaz, P.
in Industrial
Enzymes: Structure, Function and Applications (2007) Chpt.
5, 65-82, Springer NL, Polaina, Julio; MacCabe, Andrew P.
(Eds.), XII, 642 p., Hardcover. ISBN: 978-1-4020-5376-4
La
Química de la
vida a escala atómica
Hermoso,
J.A., Sanz-Aparicio, J.A. and Albert, A.
Anales de Química
(2006) 102(4), 15-22 [PDF-copy]
C-terminal Tyrosine
of Ferredoxin-NADP+ reductase in the hydride transfer processes with
NAD(P)+/H
J. Tejero, I.
Pérez-Dorado, C. Maya, M.
Martínez-Júlvez, J. Sanz-Aparicio, C.
Gómez-Moreno, J.A. Hermoso and M. Medina
Biochemistry (2005) 44, 13477-13490
Structural Analysis
of Interactions for Complex Formation between Ferredoxin-NADP+
Reductase and Its Protein Partners
Mayoral, T., Martinez-Julvez, M.,
Perez-Dorado, I., Sanz-Aparicio, J., Gomez-Moreno, C., Medina, M. and
Hermoso, J.A.
Proteins: Structure, Function, and
Bioinformatics (2005) 59, 592-602
Probing the
Determinants of Substrate Specificity of a Feruloyl Esterase, AnFaeA,
from Aspergillus niger
C.B. Faulds, R. Molina, R.
Gonzalez, F. Husband, N. Juge, J. Sanz-Aparicio and J. A. Hermoso
FEBS Journal (2005) 272, 4362-4371
Rat liver betaine
homocysteine S-methiltransferase equilibrium unfolding: Insights into
intermediate structure through tryptophan substitutions
Garrido, F., Gasset, M.,
Sanz-Aparicio, J., Alfonso, C. and Pajares, M.A.
Biochemical Journal (2005) 391, 589-599
The Crystal
Structure of Feruloyl Esterase A from Aspergillus niger
Suggests
Evolutive Functional Convergence in Feruloyl Esterase Family
Hermoso, J.A., Sanz-Aparicio, J.,
Molina, R., Juge, N., Gonzalez, R. and Faulds, C.B.
Journal of Molecular Biology (2004) 338,
495-506
Structural aspects
on rat liver S-adenosylmethionine synthesis
Pajares, M.A., Gasset, M.,
Sanz-Aparicio, J., Calvete, J.J. and Rodriguez Arrondo, J.L.
Advances in Biological Chemistry (2003)
2, 31-41
Active-site-mutagenesis study of
rat liver betaine-homocysteine S-methyltransferase
González, B.,
Campillo, N., Garrido, F., Gasset, M., Sanz-Aparicio, J. and Pajares,
M.A.
Biochem. J. (2003) 370, 945-952
Involvement of the Pyrophosphate
and the 2'-Phosphate Binding Regions of Ferredoxin-NADP+
Reductase in
Coenzyme Specificity
Tejero, J., Martinez-Julvez, M.,
Mayoral, T., Luquita, A., Sanz-Aparicio, J., Hermoso, J.A., Hurley,
J.K., Tollin, G., Gómez-Moreno, C. and Medina, M.
Journal of Biological Chemistry (2003)
278, 49203-49214
Crystal Structures
of Methionine Adenosyltransferase Complexed with Substrates and
Products Reveal the Methionine-ATP Recognition and Give Insights into
the Catalytic Mechanism
González, B., Pajares,
M.A., Hermoso, J.A., Guillerm, D., Guillerm, G. and Sanz-Aparicio, J.
Journal of Molecular Biology (2003) 331,
407-416
Crystallization and
preliminary X-ray study of recombinant betaine-homocysteine
S-methyltransferase from rat liver
González, B., Pajares,
M.A., Too, H.-P., Garrido, F., Blundell, T.L. and Sanz-Aparicio, J.
Acta Crystallographica (2002) D58,
1507-1510
Probing the role of
glutamic acid 139 of Anabaena ferredoxin-NADP+
reductase in the
interaction with substrates
Faro, M., Frago, S., Mayoral, T.,
Hermoso, J.A., Sanz-Aparicio, J., Gómez-Moreno, C. and
Medina, M.
European Journal of Biochemistry (2002)
269, 4938-4947
Mechanism of
Coenzyme Recognition and Binding Revealed by Crystal Structure Analysis
of Ferredoxin-NADP+ Reductase Complexed with
NADP+
Hermoso, J.A., Mayoral, T., Faro,
M., Gómez-Moreno, C., Sanz-Aparicio, J. and Medina, M.
Journal of Molecular Biology (2002) 319,
1193-1142
Probing the
Determinants of Coenzyme Specificity in Ferredoxin-NADP+
Reductase by
Site-directed Mutagenesis
Medina, M., Luquita, A., Tejero,
J., Hermoso, J., Mayoral, T., Sanz-Aparicio, J., Grever, K. and
Gómez-Moreno, C.
Journal of Biological Chemistry (2001)
276, 11902-11912
Role of a Cluster of Hydrophobic
Residues Near the FAD Cofactor in Anabaena
PCC 7119 Ferredoxin-NADP+
Reductase for Optimal Complex Formation and Electron Transfer to
Ferredoxin
Martínez-Júlvez,
M., Nogués, I., Faro, M., Hurley, J.K., Brodie, T.B.,
Mayoral, T., Sanz-Aparicio, J., Hermoso, J., Stankovich, M.T., Medina,
M., Tollin, G. and Gómez-Moreno, C.
Journal of Biological Chemistry (2001)
276, 27498-27510
Direct Evolution of
β-Glucosidase A from Paenibecillus
polymyxa to Thermal
Resistance
Gonzalez-Blasco, G.,
Sanz-Aparicio, J., Gonzalez, B., Hermoso, J.A. and Polaina, J.
Journal of Biological Chemistry (2000)
275, 13708-13712
The Crystal
Structure of Tetrameric Methionine Adenosyltransferase from Rat Liver
Reveals the Methionine-binding site
González, B., Pajares,
M.A., Hermoso, J.A., Alvarez, L., Garrido, F., Sufrin, J.R. and
Sanz-Aparicio, J.
Journal of Molecular Biology (2000) 300,
363-375
Structural Basis of the Catalytic
Role of Glu301 in Anabaena
PCC 7119 Ferredoxin-NADP+ Reductase
Revealed
by X-Ray Crystallography
Mayoral, T., Medina, M.,
Sanz-Aparicio, J., Gomez-Moreno, C. and Hermoso, J.
Proteins: Structure, Function, and
Genetics (2000) 38, 60-69
Role of Arg100 and
Arg264 from Anabaena
PCC 7119 Ferredoxin-NADP+ Reductase
for Optimal
NADP+ Binding and Electron Transfer
Martinez-Julvez, M., Hermoso, J.,
Hurley, J.K., Mayoral, T., Sanz-Aparicio, J., Tollin, G., Gomez-Moreno,
C. and Medina, M.
Biochemistry (1998) 37, 17680-17691
Crystal Structure of
beta-Glucosidase A from Bacillus
polymyxa: Insights into the Catalytic
Activity in Family 1 Glycosyl Hydrolases
Sanz-Aparicio, J., Hermoso, J.A.,
Martinez-Ripoll, M., Lequerica, J.L. and Polaina, J.
Journal of Molecular Biology (1998) 275,
491-502
Structural Basis of
Increased Resistance to Thermal Denaturation Induced by Single Amino
Acid Substitution in the Sequence of β-Glucosidase A From Bacillus
polymyxa
Sanz-Aparicio, J., Hermoso, J.A.,
Martinez-Ripoll, M., Gonzalez, B., Lopez-Camacho, C. and Polaina, J.
Proteins: Structure, Function, and
Genetics (1998) 33, 567-576
Purification,
Crystallization and Preliminary X-ray Diffraction Studies of
C-Phycocyanin and Allophycocyanin from Spirulina platensis
Moreno, A., Bermejo, R.,
Talavera, E., Alvarez-Pez, J.M., Sanz-Aparicio, J. and Romero, A.
Acta
Crystallographica (1997) D53, 321-326
The
Crystal Structure of Canavalia
brasiliensis Lectin Suggest a
Correlation Between its Quaternary Conformation and its Distinct
Biological Properties from Concanavalin A
Sanz-Aparicio, J., Hermoso, J.A.,
Grangeiro, T.B., Calvete, J.J. and Cavada, B.S.
FEBS Letters (1997) 405, 114-118
Macromoléculas
biológicas: Estructura tridimensional
Martínez-Ripoll, M.,
Romero, A. and Sanz-Aparicio, J.
Investigación y Ciencia (1995)
222, 83-84
Crystallizacion and Preliminary
X-ray Diffraction Analysis of a Type I β-Glucosidase Encoded
by the
bglA Gene of Bacillus
polymyxa
Sanz-Aparicio, J., Romero, A.,
Martinez-Ripoll, M., Madarro, A., Flors, A. and Polaina, J.
Journal of Molecular Biology (1994) 240,
267-270
The
Use of
Protein
Homologues in the Rotation Function
Aguilar, C.F., Newman,
M.P., Sanz-Aparicio, J., Cooper, J.B., Tickle, I.J. and Blundell, T.L.
Acta Crystallographica (1993) A49,
306-315 (doi:10.1107/S010876739200847X)
Synthesis,
Structural, Conformational and Pharmacological Study od Esters Derived
from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9a-ol as potentail
analgesics.
Iriepa, I., Gil-Alberdi, B., Gálvez, E., Sanz-Aparicio, J.,
Fonseca, I. Orjales, A. Berisa, A. and Labeaga, C.
Journal
of Physic Organic Chemistry (1998) 11, 125-132
A generalized and efficient preparation of a novel class of macrocyclic
bis(guanidines) from cyclic bis(catbodiimides)
Molina, J., Alajarín, M., Sanchez-Andrade, P.,
Sanz-Aparicio, J. and Martínez-Ripoll,
M.
Journal
of Organic Chemistry (1998) 63,2922-2927
Enantiomerically pure α-alkalidene β-amino
esters from asymmetric
addition of metal dienolates to N-sulfinylimines
García-Ruano, J.L., Fernández, I., del Prado
Catalina, M., Hermoso, J.A., Sanz-Aparicio, J. and
Martínez-Ripoll, M.
Journal
of Organic Chemistry (1998) 63, 7157-7161
10H+-2,3-Benzo-1,4-dioxa-7,10,13-triazacyclopentadec-2-ene-6,14-dione
Picrate Hydrate (1/1/1)
G. Hundal, S. Kumar, M.S. Hundal, H. Singh, J. Sanz-Aparicio and M.
Martinez-Ripoll
Acta
Crystallographica (1997) C53, 799-801 (doi:10.1107/S0108270196015041)
Synthetic Ionophores. 13. Pyridine-Diamide-Diester Receptors:Remarkable
Effect of Amide Substituents on Molecular Organization and Ag+
Selectivity
Kumar, S., Singh Hundal, M., Kaur, N., Singh, R., Singh, H., Hundal,G.,
Martinez-Ripoll, M. and Sanz-Aparicio, J.
Journal
of Organic Chemistry (1996) 61, 7819-7825
Structure-Based Rationalization of the Ionophore Character of
Lead-Selective Amide-Ether-Amine-Containing Macrocycles: 2,3-Benzo-
1,4-dioxa- 7,11,15 -triazacycloheptadec- 2-ene-6,16-dione and
2,3-Benzo-1,4-dioxa-7,10,13-triazacyclopentadec-2-ene-6,14-dione
Hundal, G., Martinez-Ripoll, M., Sanz-Aparicio, J., Hundal, M.S.,Singh,
H., Kumar, S. and Singh, R.
Acta
Crystallographica (1996) C52, 1232-1236
Remarkable Effect of Amide Substituents on molecular Organisation of
Silver Selective Pyridine-Diamide-Diester Receptors
Kumar, S., Hundal, M.S., Kaur, N., Singh, R., Singh, H., Hundal,
G.,Martinez-Ripoll, M. and Sanz-Aparicio, J.
Tetrahedron
Lettetrs (1995) 36, 9543-954
1-Aminocyclohexene-2,4-dicarbonitrile derivatives. Synthesis and
structural study
Lorente, A., Galan, C., Fonseca, I. and Sanz-Aparicio, J.
Canadian
Journal of Chemistry (1995) 73,
1546-1555
Synthesis, Structure, and Pharmacological Evaluation of the
Stereoisomers of Furnidipine
Alajarin, R., Vaquero, J.J., Alvarez-Builla, J., Pastor, M., Sunkel,
C., Fau-Casa-Juana, M., Priego, J., Statkow, P.R., Sanz-Aparicio,
J. and Fonseca, I.
Journal
of Medicinal Chemistry (1995) 38, 2830-2841
2,3-Benzo-11-(2-cyanoethyl)-1,4-dioxa-7,11,15-triazacycloheptadec-2ene-6,16-dione-Water
(1/1)
Hundal, G., Hundal, M.S., Kumar, S., Singh, H. and Sanz-Aparicio,
J.
Acta
Crystallographica (1995) C51, 1459-1460
Synthesis and Structural, Conformational, Biochemical, and
Pharmacological Study of New Compounds Derived from Tropane-3-spiro
-4'(5')imidazolione as Potential 5-HT3 Receptor Antagonists
Whelan, B.A., Iriepa, I., Galvez, E., Orjales, A., Berisa, A., Labeaga,
L., Garcia, A.G., Uceda, G., Sanz-Aparicio, J. and Fonseca,
I.
Journal
of Pharmaceutical Sciences (1995) 84, 101-106
Synthesis and Structure of New Substituted
2-Dicyanomethylene-1,2dihydropyridines
Fuentes, L., Marquez, C., Contreras, M.C., Lorenzo, M.J., Fonseca, I.,
Sanz-Aparicio, J. and Balcazar, J.L.
Journal
of Heterocyclic Chemistry (1995) 32, 29-32
Metallic Carbonyl Complexes Containing Heterocycle Nitrogen Ligands. 2.
Tricarbonylbromo(3,3'-R-2,2'-biquinoline)Rhenium(I) Compounds
Moya, S.A, Guerrero, J., Pastene, R., Schmidt, R., Sariego, R.,
Sartori, R., Sanz-Aparicio, J., Fonseca, I., and Martinez-Ripoll,
M.
Inorganic
Chemistry (1994) 33, 2341-2346
New Iridium(I) and Diiridium(I,III) Complexes containing Thiolate
Ligands. Crystal Structures of [(cod)Cl(SC6F5)Ir(u-SC6F5)2Ir(cod)] and
[(Ir(uSC6F5)(CO)2)2] (cod)=cycloocta-1,5-diene)
Fonseca, I., Hernandez, E., Sanz-Aparicio, J., Terreros, P. and
Torrens, H.
Journal
of the Chemical Society, Dalton (1994) 781-783
Addition compounds of dichlorodioxomolybdenum(VI) from hydrochloric
acid solutions of molybdenum trioxide. Crystal structure of
dichlorodioxodiaquamolybdenum(VI) bid(2,5,8-trioxanonane)
Arnaiz, F.J., Aguado, R., Sanz-Aparicio, J. and
Martinez-Ripoll, M.
Polyhedron
(1994) 13, 2745-2749
Synthesis and Structure of New Pyrido[2,3-d]pyrimidine Derivatives with
Calcium Channel Antagonist Activity
Pastor, A., Alajarin, R., Vaquero, J.J., , J., CasaJuana, M.F., Sunkel,
C., Priego, J.G., Fonseca, I. and Sanz-Aparicio, J.
Tetrahedron
(1994) 50, 8085-8098
Synthesis and structural and conformational study of 3,7-dimethyl- 3,
7-diazabicyclo[3.3.1]nonan-9-one oxime and its tautomer imine N-oxide
Fernandez, M.J., Huertas, R., Galvez, E., Sanz-Aparicio, J., Fonseca,
I. and Bellanato, J.
Journal
of the Molecular Structure (1994) 323, 85-91
Conformational Study of 2,4-Diaryl-3-azabicyclo[3.3.1]nonan-9-ones and
Their 3-Methyl Derivatives by Quantum Mechanical Calculations, NMR and
Xray Crystallography
Arias, M.S., Smeyers, Y.G., Fernandez, M.J., Smeyers, N.J., Galvez, E.,
Fonseca, I. and Sanz-Aparicio, J.
Journal
of Organic Chemistry(1994) 59, 2565-2569
Synthesis and structural, conformational and pharmacological study of
some esters derived from 3-β-hydroxytropan-3-α-
carboxylic
acid
Burgos, C., Izquierdo, M.L., Arias, M.S., Galvez, E., Matesanz, E.,
Martinez-Ripoll, M., Sanz-Aparicio, J., Fonseca, I., Bellanato, J. and
Lopez Ruiz, P.
Journal
of the Molecular Structure (1993) 301, 95-105
Synthesis and Structural, Biochemical, and Pharmacological Study of
3β-Acyloxy-3α-methoxycarbonyltropane Derivatives
Galvez, E., Izquierdo, M.L., Burgos, C., Arias, M.S., Sanz-Aparicio,
J., Fonseca, I., Gago, F., Baldominos, G., Lopez, P. and Prieto, J.C.
Journal
of Pharmaceutical Sciences (1993) 82, 794-798
Rotational Dynamics of 1,6-Diphenyl-1,3,5-hexatriene and Derivatives
from Fluorescence Depolarization
Mateo, C.R., Lillo, M.P., Brochon, J.C., Martinez-Ripoll, M.,
Sanz-Aparicio, J. and Acuna, A.U.
Journal
of the Physical Chemistry (1993), 97, 3486-3491
Synthesis and Chromatographic Separation of the Stereoisomers of
Furnidipine
Alajarin, R., Alvarez-Builla, J., Vaquero, J.J., Sunkel, C., Fau, M.,
Statkow, P.R. and Sanz-Aparicio, J.
Tetrahedron:
Assymetry (1993) 4, 617-620
Synthesis, Structural, Conformational and Biochemical Study of some
3β-Acyloxytropan-3α-carboxilic Acid Hydrochlorides
Burgos, C., Galvez, E., Izquierdo, M.L., Arias, M.S., Sanz-Aparicio,
J., Fonseca, I. and Lopez, P.
Journal
of the Heterocyclic Chemistry (1992) 29, 1821-1827
Structural and conformational study of
3-methyl-2,4-diphenyl-3azabicyclo[3.3.1]nonan-9α-ol
Iriepa, I., Gil-Alberdi, B., Galvez, E., Sanz-Aparicio, J., Fonseca, I.
and Bellanato, J.
Journal
of the Molecular Structure (1993) 293, 49-54
Structural and conformational study of some N'-substituted benzoyl
derivatives of the
3-β-amino-3-α-carbamoyl-N-8-substituted
nortropanes
Izquierdo, M.L., Galvez, E., Burgos, C., Arias, M.S., Sanz-Aparicio,
J., Fonseca, I. and Bellanato, J.
Journal
of the Molecular Structure (1993) 291, 1-10
Synthesys and structural and conformational study of
3α-methoxycarbonyl-3β-(3',4',5'-trimethoxybenzamido)-N8
-substituted nortropanes
Burgos, C., Izquierdo, M.L., Arias, M.S., Galvez, E., Sanz-Aparicio,
J. and Fonseca, I.
Journal
of the Molecular Structure (1992) 267, 79-86
Structural study of 3-α(p-tolylamino)-N-phenethylnorgranatane
Fernandez, M.J., Huertas, R., Galvez, E., Sanz-Aparicio, J.
and Fonseca, I.
Journal
of the Molecular Structure (1992) 266, 283-288
Structural Study of Benzidamine Salicylate in the Solid State and in
Solution
Galvez, E., Fernandez-Sanchez, C., Sanz-Aparicio, J., Florencio, F.,
Fernandez-Navarro, E. , Bellanato, J.
Journal
of Pharmaceutical Sciences (1992) 81, 94-98
Synthesis, and Structural, Conformational and Pharmacological Studies
of new Fentanyl Derivatives of the Norgranatane System
Fernandez, M.J., Huertas, R.M., Galvez, E., Orjales, A., Berisa, A.,
Labeaga, L., Gago, F., Fonseca, I., Sanz-Aparicio, J., Cano, F.H.,
Albert, A. and Fayos, J.
Journal
of the Chemical Society, Perkin Trans. 2 (1992) 687-695
Structural Characterization of (+-)-3-Aryl-1-azabicyclo[2.2.2]octan ols
by Two-Dimensional NMR Spectroscopy and X-Ray Crystallography. I.
Arias, M.S., Cosme, A., Galvez, E., Florencio, F., Fonseca, I. and
Sanz-Aparicio, J.
Magnetic
Resonance in Chemistry (1991) 29, 1130-1139
Crystal and molecular structure of 6-phenyl-13H-pyrimido[4,3-b:6,1b]
bis-benzothiazolium-12 triiodide
Ramos, T., Avendano, C., Elguero, J., Florencio, F. and
Sanz-Aparicio, J.
Journal
of Crystallographic and Spectroscopic Research (1991) 21,
179-182
Synthesis and Structural, Conformational, and Pharmacological Study of
Some Esters Derived from 3-Phenethyl-3-azabicyclo[3.2.1]octan-8-
beta-ol and the Corresponding N-Endo-methyl Quaternary
Derivatives
Izquierdo, M.L., Arias, M.S., Galvez, E., Rico, B., Ardid, I.,
Sanz-Aparicio, J., Fonseca, I., Orjales, A. and Innerarity, A.
Journal
of Pharmaceutical Sciences (1991) 80, 554-558
Synthesis and structural and conformational study of some esters
derived from
8-α-hydroxy-3-phenetyl-3-azabicyclo[3.2.1]octan-8-
βcarboxylic acid.
Diez, M., Izquierdo, M.L., Galvez, E., Arias, M.S., Fonseca, I. and
Sanz-Aparicio, J.
Journal
of the Molecular Structure (1991), 246,
339-357
Synthesis, structural, conformational and pharmacological study of
N2'-acyloxy alkylnorgranatanones
Iriepa, I., Lorente, A., Galvez, E., Florencio, F., Sanz-Aparicio, J.,
Orjales, A. and Innerarity, A.
European
Journal of Medicinal Chemistry (1990) 25, 497-506
Synthesis and Structural Study of Dichloro
Di-2-benzothiazolylphenylmethanol Zinc(II)
Ramos, M.T., Avendano, C., Elguero, J., Florencio, F. and
Sanz-Aparicio, J.
Inorganic
Chimica Acta (1990) 174, 169-173
Synthesis, Structural and Conformational Study of 6-Hydroxy (or
Acyloxy) Derivatives of the 1,3-Dimethyl-1,3-diazoniatricyclo [3.3.1.1
37]decane System
Fernandez, M.J., Galvez, E., Lorente, A., Camunas, J.A., Sanz-Aparicio,
J. and Fonseca, I.
Journal
of Heterocyclic Chemistry (1990) 27, 1355-1359
Early-Transition-Metal Ketenimine Complexes. Synthesis, Reactivity, and
Structural Characterization of Complexes with
η2(C,N)-Ketenimine Groups
Bound to the Halogenobis(trimethylsilyl) cyclopentadienyl)niobium Unit.
X-ray Structure of Nb(η5-C5H4Si)
Antinolo, A., Fajardo, M., Lopez, C., Otero, A., Mourad, Y., Mugnier,
Y., Sanz-Aparicio, J., Fonseca, I. and Florencio, F.
Organometallics
(1990) 9, 2919-2925
Two Rings in One Step: A Novel 1,2,4-Triazolo[1,5-a]pyridone with an
Unusual Crystal Structure
Martin, N., Quinteiro, M., Seoane, C., Soto, J.L., Fonseca, I.,
Florencio, F. and Sanz-Aparicio, J.
Journal
of Organic Chemistry (1990) 55, 2259-2262
Heteroaryl Stabilised Azinium Ylides. 1,3,4-thiadiazole as Stabilising
Group
Carceller, R., Garcia-Navio, J.L., Izquierdo, M.L., Alvarez-Builla, J.,
Sanz-Aparicio, J. and Florencio, F.
Heterocycles
(1989) 29, 1877-1889
Synthesis, Structural and Conformational Study of Some Esters Derived
from 8-Phenethyl-8-azabicyclo[4.3.1]decan-10α-ol
Galvez, E., Arias, M.S., Rico, B., Ardid, I., Florencio, F. and
Sanz-Aparicio, J.
Journal
of Heterocyclic Chemistry (1989) 26, 965-970
Synthesis, Structural and Conformational Study of 4-α-(or
β)-
p-Chlorobenzoyloxy-l-azaadamantane Hydrochloride
Fernandez, M.J., Galvez, E., Lorente, A., Soler, J.A., Florencio, F.
and Sanz-Aparicio, J.
Journal
of Heterocyclic Chemistry (1989) 26, 349-353
Tris(2-Benzothienyl)(methoxy)methane: a Trisheteroarylmethane with a
Molecular Propeller Conformation in the Solid State
Avendano, C., de Diego, C., Elguero, J., Florencio, F. and
Sanz-Aparicio, J.
Journal
of the Chemical Research (S) (1989) 190-191
Structural and spectroscopic study of condensed piperidine bicyclanols.
3-Phenethyl-3-azabicyclo[3.2.1]octan-8-α-ol
Galvez, E., Arias, M.S., Ardid, I., Florencio, F., Sanz-Aparicio, J.,
Bellanato, J. and Garcia-Ramos, J.V.
Journal
of the Molecular Structure (1989) 196, 307-316
Synthesis and structural study of tropane benzamines. Part III.
N-(8-Isopropyl-nortropan-3-β-yl)-2-methoxy-4-amino-5-
chlorobenzamide
Cabezas, N., Martinez, M., Galvez, E., Arias, M.S., Florencio, F. and
Sanz-Aparicio, J.
Journal
of the Molecular Structure (1989) 197, 59-72
Tautomerism of bis(2-benzothiazolyl)arylmethanes
Ramos, M.T., Avendano, C., Elguero, J., Jimeno, M.L., Bellanato, J.,
Florencio, F. and Sanz-Aparicio, J.
Heterocycles
(1989) 29, 165-180
Structural and conformational study of
9-(2'-hydroxyethyl)-9azabicyclo[3.3.1]nonan-3-β-ol
Iriepa, I., Arias, M.S., Lorente, A., Galvez, E., Florencio, F. and
Sanz-Aparicio, J.
Journal
of the Molecular Structure (1989) 192, 15-27
Reactions of 1,2-diaminobenzimidazoles with β-dicarbonyl
compounds
Romano, C., de la Cuesta, E., Avendano, C., Florencio, F. and Sanz
Aparicio, J.
Tetrahedron
(1988) 44, 7185-7192
A Novel Ring System: 6a-Aminofuro[2,3-b]furans
Aran, V.J., Martin, N., Seoane, C., Soto, J.L., Sanz-Aparicio, J. and
Florencio, F.
Journal
of Organic Chemistry(1988) 53, 5341-5343
Synthesis and structural study of 9-(2'-hydroxyethyl)-9-azabicyclo
[3.3.1]nonan-3α-ol
Iriepa, I., Lorente, A., Arias, M.S., Galvez, E., Florencio, F. and
Sanz-Aparicio, J.
Journal
of the Molecular Structure (1988) 174, 273-280
Preparation and structural characterization of new alkoxo- and
(alkoxo)(amido)(imido)-niobium(V) compounds. Crystal structure of
[NbCl(η-OMe) [N(SiMe3)2](NSiMe3)]2
Antiñolo, A., Otero, A., Urbanos, F., Garcia-Blanco, S.,
Martinez-Carrera, S. and Sanz-Aparicio, J.
Journal
of the Organometalic Chemistry (1988) 350, 25-34
Lattice-Energy Calculations on Organometallic Compounds
Sanz-Aparicio, J., Martinez-Carrera, S. and Garcia-Blanco, S.
Acta
Crystallographica (1988) B44, 259-262
New Tantalum Ylide Complexes: Crystal and Molecular Structure of
(η5C5Me5) Cl4Ta.(CH2=PMePh2) Containing a Neutral Phosphorus
Ylide
Fandos, R., Gomez, M., Royo, P., Garcia-Blanco, S., Martinez-Carrera,
S. and Sanz-Aparicio, J.
Organometallics
(1987) 6, 1581-1583
Structure of Dicarbonyl(η5-cyclopentadienyl)(O,O'-diethyl
dithiophosphato) iron(II)
Sanz-Aparicio, J., Martinez-Carrera, S. and Garcia-Blanco, S.
Acta
Crystallographica (1987) C43, 2009-2011
Mixed Oxides of the System M(V)-Te(IV)-O2 (M= Nb, Ta, Sb); II. Crystal
Structure of Ta2Te2O9 Martinez-Carrera, S., Sanz-Aparicio, J., Pico,
C., Gaitan, M., Jerez, A. and Veiga, M.L.
Materials
Research Bulletin (1987) 22, 1405-1412
Structure of (η5-Cyclopentadienyl)(dicarbonyl)(O,O'-diisopropyl
dithiophosphato)-iron(II)
Sanz-Aparicio, J., Martinez-Carrera, S. and Garcia-Blanco, S.
Acta
Crystallographica (1986) C42, 1121-1123
Crystal Structure of
(η5-pentamethylcyclopentadienyl)(O,O'-diiso
propyldithiophosphato) (dicarbonyl)-iron(II), FeS2PO4C18H29
Sanz-Aparicio, J., Martinez-Carrera, S. and Garcia-Blanco, S.
Zeitschrift für Kristallographie (1986) 175, 195-202