Publications
Structure-based discovery of hydrocarbon-stapled paxillin peptides that block FAK scaffolding in cancer
Lauren
Reyes, Lena Naser, Warren S. Weiner, Darren Thifault, Erik Stahl, Liam
McCreary, Rohini Nott, Colton Quick, Alex Buchberger, Carlos Alvarado,
Andrew Rivera, Joseph A. Miller, Ruchi Khatiwala, Brian R. Cherry,
Ronald Nelson, Jose M. Martin-Garcia, Nicholas Stephanopoulos, Raimund
Fromme, Petra Fromme, William Cance & Timothy Marlowe
Nature Communications (2025) 16, article number 2060 (doi:
10.1038/s41467-025-57196-9)
Cyclic Olefin Copolymer-Based Fixed-Target Sample Delivery Device for Protein X-ray Crystallography
Manna A, Sonker M, Koh D, Steiger M, Ansari A, Hu H, Quereda-Moraleda
I, Grieco A, Doppler D, de Sanctis D, Basu S, Orlans J, Rose SL, Botha
S, Martin-Garcia JM, Ros A.
Anal Chem. (2024) (doi: 10.1021/acs.analchem.4c03484)
A small molecule cryptotanshinone induces non-enzymatic NQO1-dependent
necrosis in cancer cells through the JNK1/2/Iron/PARP/calcium pathway
Hou Y, Zhong B, Zhao L, Wang H, Zhu Y, Wang X, Zheng H, Yu J, Liu G, Wang X, Martin-Garcia JM, Chen X
Acta Pharmaceutica Sinica B. (2024) (doi: 10.1016/j.apsb.2024.12.005)
New insights into the function and molecular mechanisms of Ferredoxin-NADP+ reductase from Brucella ovis
Moreno A, Quereda-Moraleda I, Lozano-Vallhonrat C,
Buñuel-Escudero M, Botha S, Kupitz C, Lisova S, Sierra R,
Mariani V, Schleissner P, Gee LB, Dörner K, Schmidt C, Han H,
Kloos M, Smyth P, Valerio J, Schulz J, de Wijn R, Melo DVM, Round A,
Trost F, Sobolev E, Juncheng E, Sikorski M, Bean R,
Martínez-Júlvez M, Martin-Garcia* JM, Medina M
Arch Biochem Biophys. (2024) (doi: 10.1016/j.abb.2024.110204)
Innovative Strategies in X-ray Crystallography for Exploring Structural Dynamics and Reaction Mechanisms in Metabolic Disorders
Grieco A, Quereda-Moraleda I, Martin-Garcia* JM
J Pers Med. (2024) (doi: 10.3390/jpm14090909)
Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations
Grieco A, Boneta S, Gavira JA, Pey AL, Basu S, Orlans J, Sanctis D, Medina M, Martin-Garcia* JM
Protein Sci. (2024) (doi: 10.1002/pro.4957)
Insights into the pathogenesis
of primary hyperoxaluria type I from the structural dynamics of
alanine:glyoxylate aminotransferase variants Vankova, P.,
Pacheco-Garcia, J. L., Loginov, D. S., Gómez-Mulas, A.,
Kádek, A., Martín-Garcia, J. M., Salido, E., Man, P.,
& Pey, A. L.
FEBS letters (2024) (doi: 10.1002/1873-3468.14800)
Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSF
Grieco, A., Ruiz-Fresneda, M. A., Gómez-Mulas, A.,
Pacheco-García, J. L., Quereda-Moraleda, I., Pey, A. L., &
Martin-Garcia*, J. M.
FEBS letters (2023) 597(21), 2687–2698 (doi: 10.1002/1873-3468.14738)
Heterogeneity in M. tuberculosis β-lactamase inhibition by Sulbactam
Malla TN, Zielinski K, Aldama L, Bajt S, Feliz
D, Hayes B, Hunter M, Kupitz C, Lisova S, Knoska J, Martin-Garcia JM,
Mariani V, Pandey S, Poudyal I, Sierra RG, Tolstikova A, Yefanov O,
Yoon CH, Ourmazd A, Fromme P, Schwander P, Barty A, Chapman HN,
Stojkovic EA, Batyuk A, Boutet S, Phillips GN Jr, Pollack L, Schmidt M
Nature Communications (2023) 14(1), 5507 (doi: 10.1038/s41467-023-41246-1)
Catalytic process of anhydro-N-acetylmuramic acid kinase (AnmK) from Pseudomonas aeruginosa
Amr M. El-Araby, Eva Jiménez-Faraco, Rhona Feltzer, Jose M.
Martin-Garcia, Bhaskara Rao Karri, Balajee Ramachandran, Choon Kim, Jed
F. Fisher, Juan A. Hermoso, Shahriar Mobashery
Journal of Biological Chemistry (2023)
(doi:
10.1016/j.jbc.2023.105198)
Modular Droplet Injector for Sample
Conservation Providing New Structural Insight for the Conformational
Heterogeneity in the Disease-Associated NQO1 Enzyme
D.
Doppler, M. Sonker, A. Egatz-Gomez, A. Grieco, S. Zaare, R. Jernigan,
J.D. Meza-Aguilar, M.T. Rabbani, A. Manna, R. Alvarez, K. Karpos, J.C.
Villarreal, G. Nelson, J-H Yang, J. Carrion, K. Morin, G.K. Ketawala,
A.L. Pey, M.A. Ruiz-Fresneda, J.L. Pacheco‐Garcia, J.A. Hermoso, R.
Nazari, R. Sierra, M.S. Hunter, A. Batyuk, C.J. Kupitz, R.E. Sublett,
S. Lisova, V. Mariani, S. Boutet, R. Fromme, T.D. Grant, S. Botha, P.
Fromme, R.A. Kirian, J.M. Martin-Garcia*, A. Ros*
Lab on a Chip (2023) 23, 3016–3033 (doi: 10.1039/D3LC00176H)
Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser
Jernigan
RJ, Logeswaran D, Doppler D, Nagaratnam N, Sonker M, Yang JH, Ketawala
G, Martin-Garcia JM, Shelby ML, Grant TD, Mariani V, Tolstikova A,
Sheikh MZ, Yung MC, Coleman MA, Zaare S, Kaschner EK, Rabbani MT,
Nazari R, Zacks MA, Hayes B, Sierra RG, Hunter MS, Lisova S, Batyuk A,
Kupitz C, Boutet S, Hansen DT, Kirian RA, Schmidt M, Fromme R, Frank M,
Ros A, Chen JJ, Botha S, Fromme P.
Structure. (2023) 31, 138-151 (doi: 10.1016/j.str.2022.12.009)
Electrically stimulated droplet injector for reduced sample consumption in serial crystallography
Sonker M,
Doppler D, Egatz-Gomez A, Zaare S, Rabbani MT, Manna A, Cruz Villarreal
J, Nelson G, Ketawala GK, Karpos K, Alvarez RC, Nazari R, Thifault D,
Jernigan R, Oberthür D, Han H, Sierra R, Hunter MS, Batyuk A,
Kupitz CJ, Sublett RE, Poitevin F, Lisova S, Mariani V, Tolstikova A,
Boutet S, Messerschmidt M, Meza-Aguilar JD, Fromme R, Martin-Garcia JM,
Botha S, Fromme P, Grant TD, Kirian RA, Ros A.
Biophysical Reports (NY) (2022) 2(4):100081 (doi: 10.1016/j.bpr.2022.100081)
Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis
Nagaratnam N,
Martin-Garcia JM, Yang JH, Goode MR, Ketawala G, Craciunescu FM, Zook
JD, Sonowal M, Williams D, Grant TD, Fromme R, Hansen DT, Fromme P
PLoS One (2022) 17(8), e0267370 (doi: 10.1371/journal.pone.0267370)
Purification, characterization, and preliminary serial crystallography
diffraction advances structure determination of full-length human
particulate guanylyl cyclase A receptor
Zhang S, Hansen DT, Martin-Garcia JM, Zook JD, Pan S, Craciunescu FM, Burnett JC Jr, Fromme P
Scientific Reports (2022) 12(1), 11824 (doi: 10.1038/s41598-022-15798-z)
Serial macromolecular crystallography at ALBA Synchrotron Light Source
J. M. Martin-Garcia,
S. Botha, H. Hu, R. Jernigan, A. Castellví, S. Lisova, F. Gil,
B. Calisto, I. Crespo, S. Roy-Chowdhury, A. Grieco, G. Ketawala, U.
Weierstall, J. Spence, P. Fromme, N. Zatsepin, D. R. Boer and X. Carpena
Journal of Synchrotron Radiation (2022) 29 (doi:10.1107/S1600577522002508)
Co-flow injection for serial crystallography at X-ray free-electron lasers
D. Doppler, M. T. Rabbani, R. Letrun, J. Cruz Villarreal, D. H. Kim, S.
Gandhi, A. Egatz-Gomez, M. Sonker, J. Chen, F. H. M. Koua, J. Yang, M.
Youssef, V. Mazalova, S. Bajt, M. L. Shelby, M. A. Coleman, M. O.
Wiedorn, J. Knoska, S. Schön, T. Sato, M. S. Hunter, A.
Hosseinizadeh, C. Kuptiz, R. Nazari, R. C. Alvarez, K. Karpos, S.
Zaare, Z. Dobson, E. Discianno, S. Zhang, J. D. Zook, J. Bielecki, R.
de Wijn, A. R. Round, P. Vagovic, M. Kloos, M. Vakili, G. K. Ketawala,
N. E. Stander, T. L. Olson, K. Morin, J. Mondal, J. Nguyen, J. D.
Meza-Aguilar, G. Kodis, S. Vaiana, J. M. Martin-Garcia,
V. Mariani, P. Schwander, M. Schmidt, M. Messerschmidt, A. Ourmazd, N.
Zatsepin, U. Weierstall, B. D. Bruce, A. P. Mancuso, T. Grant, A.
Barty, H. N. Chapman, M. Frank, R. Fromme, J. C. H. Spence, S. Botha,
P. Fromme, R. A. Kirian and A. Ros
Journal of Applied Crystallography (2022) 55 (doi: org/10.1107/S1600576721011079)
Observation
of substrate diffusion and ligand binding in enzyme crystals using
high-repetition-rate mix-and-inject serial crystallography
Suraj
Pandey, George Calvey, Andrea M. Katz, Tek Narsingh Malla, Faisal H. M.
Koua, Jose M. Martin-Garcia, Ishwor Poudyal, Jay-How Yang, Mohammad
Vakili, Oleksandr Yefanov, Kara A. Zielinski, Sasa Bajt, Salah Awel,
Katarina Doerner, Matthias Frank, Luca Gelisio, Rebecca Jernigan, Henry
Kirkwood, Marco Kloos, Jayanath Koliyadu, Valerio Mariani, Mitchell D.
Miller, Grant Mills, Garrett Nelson, Jose L. Olmos Jr, Alireza Sadri,
Tokushi Sato, Alexandra Tolstikova, Weijun Xu, Abbas Ourmazd, John C.
H. Spence, Peter Schwander, Anton Barty, Henry N. Chapman, Petra
Fromme, Adrian P. Mancuso, George N. Phillips Jr, Richard Bean, Lois
Pollack and Marius Schmidt
IUCrJ
(2021) 8, 878-895 (doi: 10.1107/S2052252521008125)
Protein Dynamics and Time Resolved Protein Crystallography at Synchrotron Radiation Sources: Past, Present and Future.
Martin-Garcia, J.M.
Crystals (2021) 11, 521 (doi: 10.3390/cryst11050521)
Structural insights into the function of the catalytically active human Taspase1
Nirupa Nagaratnam, Silvia L. Delker, Rebecca Jernigan, Thomas E.
Edwards, Janey Snider, Darren Thifault, Dewight Williams, Brent L.
Nannenga, Mary Stofega, Lidia Sambucetti, James J. Hsieh, Andrew J.
Flint, Petra Fromme, Jose M. Martin-Garcia
Structure (2021) 29, 1–13 (doi: 10.1016/j.str.2021.03.008)
Methods for Crystallization and
Structural Determination of M-T7 Protein from Myxoma Virus
Gisriel
C, Fromme P, Martin-Garcia
JM
Methods Mol Biol. (2021) 2225,
125-162 (doi:
10.1007/978-1-0716-1012-1_8)
Segmented flow generator for serial crystallography at the European
X-ray free electron laser
Echelmeier A, Cruz Villarreal J, Messerschmidt M, Kim D, Coe JD,
Thifault D, Botha S, Egatz-Gomez A, Gandhi S, Brehm G, Conrad CE,
Hansen DT, Madsen C, Bajt S, Meza-Aguilar JD, Oberthür D,
Wiedorn
MO, Fleckenstein H, Mendez D, Knoška J, Martin-Garcia JM,
Hu H, Lisova S, Allahgholi A, Gevorkov Y, Ayyer K, Aplin S, Ginn HM,
Graafsma H, Morgan AJ, Greiffenberg D, Klujev A, Laurus T, Poehlsen J,
Trunk U, Mezza D, Schmidt B, Kuhn M, Fromme R, Sztuk-Dambietz J, Raab
N, Hauf S, Silenzi A, Michelat T, Xu C, Danilevski C, Parenti A,
Mekinda L, Weinhausen B, Mills G, Vagovic P, Kim Y, Kirkwood H, Bean R,
Bielecki J, Stern S, Giewekemeyer K, Round AR, Schulz J,
Dörner K,
Grant TD, Mariani V, Barty A, Mancuso AP, Weierstall U, Spence JCH,
Chapman HN, Zatsepin N, Fromme P, Kirian RA, Ros A
Nat Commun. (2020) Sep 9;
11(1):4511 (doi:
10.1038/s41467-020-18156-7)
Construction of
gateway-compatible baculovirus expression vectors for high- throughput
protein expression and in vivo microcrystal screening
Tang
Y, Saul J, Nagaratnam N, Martin-Garcia
JM, Fromme P, Qiu J, LaBaer J
Sci Rep. (2020) Aug 7;10(1):13323
(doi:
10.1038/s41598-020-70163-2)
Enhanced X-ray diffraction of in vivo-grown μNS crystals by viscous jets at XFELs
Nagaratnam N, Tang Y,
Botha S, Saul J, Li C, Hu H, Zaare S, Hunter M, Lowry D, Weierstall U,
Zatsepin N, Spence JCH, Qiu J, LaBaer J, Fromme P, Martin- Garcia JM
Acta Crystallogr F Struct Biol Commun. (2020) Jun 1;76(Pt 6):278-289 (doi: 10.1107/S2053230X20006172)
Serial Femtosecond
Crystallography: A Decade at the Forefront in Structural Biology
Fromme, P., Graves, W.S. and Martin‐Garcia, J.M.
In
eLS, John Wiley & Sons, Ltd (Ed.). (2020) May 29; 1-17
(doi:10.1002/9780470015902.a0028964)
In cellulo crystallization of Trypanosoma brucei IMP
dehydrogenase enables the identification of genuine co-factors
Nass K, Redecke L, Perbandt M, Yefanov O, Klinge M, Koopmann R,
Stellato F, Gabdulkhakov A, Schönherr R, Rehders D,
Lahey-Rudolph
JM, Aquila A, Barty A, Basu S, Doak RB, Duden R, Frank M, Fromme R,
Kassemeyer S, Katona G, Kirian R, Liu H, Majoul I, Martin-Garcia JM,
Messerschmidt M, Shoeman RL, Weierstall U, Westenhoff S, White TA,
Williams GJ, Yoon CH, Zatsepin N, Fromme P, Duszenko M, Chapman HN,
Betzel C
Nat
Commun. (2020) Jan 30;11(1):620 (doi: 10.1038/s41467-020-14484-w)
Membrane protein megahertz
crystallography at the European XFEL
Gisriel C, Coe J, Letrun R, Yefanov OM, Luna-Chavez C, Stander NE,
Lisova S, Mariani V, Kuhn M, Aplin S, Grant TD, Dörner K, Sato
T,
Echelmeier A, Cruz Villarreal J, Hunter MS, Wiedorn MO, Knoska J,
Mazalova V, Roy-Chowdhury S, Yang JH, Jones A, Bean R, Bielecki J, Kim
Y, Mills G, Weinhausen B, Meza JD, Al- Qudami N, Bajt S, Brehm G, Botha
S, Boukhelef D, Brockhauser S, Bruce BD, Coleman MA, Danilevski C,
Discianno E, Dobson Z, Fangohr H, Martin-Garcia JM, Gevorkov Y, Hauf S,
Hosseinizadeh A, Januschek F, Ketawala GK, Kupitz C, Maia L, Manetti M,
Messerschmidt M, Michelat T, Mondal J, Ourmazd A, Previtali G, Sarrou
I, Schön S, Schwander P, Shelby ML, Silenzi A, Sztuk-Dambietz
J,
Szuba J, Turcato M, White TA, Wrona K, Xu C, Abdellatif MH, Zook JD,
Spence JCH, Chapman HN, Barty A, Kirian RA, Frank M, Ros A, Schmidt M,
Fromme R, Mancuso AP, Fromme P, Zatsepin NA
Nat Commun. (2019) Nov
4;10(1):5021 (doi: 10.1038/s41467-019-12955-3)
High- viscosity injector-based pink-beam serial
crystallography of microcrystals at a synchrotron radiation source
Martin-Garcia JM, Zhu L, Mendez D, Lee MY, Chun E, Li C, Hu H,
Subramanian G, Kissick D, Ogata C, Henning R, Ishchenko A, Dobson Z,
Zhang S, Weierstall U, Spence JCH, Fromme P, Zatsepin NA, Fischetti RF,
Cherezov V, Liu W
IUCrJ. (2019) Apr 5;6(Pt 3):412-425 (doi: 10.1107/S205225251900263X)
X-ray Emission
Spectroscopy at X-ray Free Electron Lasers: Limits to Observation of
the Classical Spectroscopic Response for Electronic Structure Analysis
Jensen SC, Sullivan B, Hartzler DA, Aguilar JM, Awel S, Bajt S, Basu S,
Bean R, Chapman HN, Conrad C, Frank M, Fromme R, Martin-Garcia JM,
Grant TD, Heymann M, Hunter MS, Ketawala G, Kirian RA, Knoska J, Kupitz
C, Li X, Liang M, Lisova S, Mariani V, Mazalova V, Messerschmidt M,
Moran M, Nelson G, Oberthür D, Schaffer A, Sierra RG, Vaughn
N,
Weierstall U, Wiedorn MO, Xavier PL, Yang JH, Yefanov O, Zatsepin NA,
Aquila A, Fromme P, Boutet S, Seidler GT, Pushkar Y
J Phys Chem Lett. (2019) Feb 7;10(3):441-446 (doi:
10.1021/acs.jpclett.8b03595)
Solving
protein structure from sparse serial microcrystal diffraction data at a
storage-ring synchrotron source
Lan TY, Wierman JL, Tate MW, Philipp HT, Martin-Garcia JM, Zhu L,
Kissick D, Fromme P, Fischetti RF, Liu W, Elser V, Gruner SM
IUCrJ. (2018) Jul 20;5(Pt 5):548-558 (doi: 10.1107/S205225251800903X)
Enzyme intermediates
captured "on the fly" by mix-and-inject serial crystallography
Olmos JL Jr, Pandey S, Martin-Garcia JM, Calvey G, Katz A, Knoska J,
Kupitz C, Hunter MS, Liang M, Oberthuer D, Yefanov O, Wiedorn M, Heyman
M, Holl M, Pande K, Barty A, Miller MD, Stern S, Roy-Chowdhury S, Coe
J, Nagaratnam N, Zook J, Verburgt J, Norwood T, Poudyal I, Xu D, Koglin
J, Seaberg MH, Zhao Y, Bajt S, Grant T, Mariani V, Nelson G,
Subramanian G, Bae E, Fromme R, Fung R, Schwander P, Frank M, White TA,
Weierstall U, Zatsepin N, Spence J, Fromme P, Chapman HN, Pollack L,
Tremblay L, Ourmazd A, Phillips GN Jr, Schmidt M
BMC
Biol. (2018) May 31;16(1):59 (doi: 10.1186/s12915-018-0524-5)
Serial
millisecond crystallography of membrane and soluble protein
microcrystals using synchrotron radiation
Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J,
Zhu L, Geiger J, Chun E, Kissick D, Hilgart MC, Ogata C, Ishchenko A,
Nagaratnam N, Roy-Chowdhury S, Coe J, Subramanian G, Schaffer A, James
D, Ketwala G, Venugopalan N, Xu S, Corcoran S, Ferguson D, Weierstall
U, Spence JCH, Cherezov V, Fromme P, Fischetti RF, Liu W
IUCrJ. (2017) May 24;4(Pt
4):439-454 (doi: 10.1107/S205225251700570X)
Bacterial expression, correct membrane targeting and
functional folding of the HIV-1 membrane protein Vpu using a
periplasmic signal peptide
Deb A, Johnson WA, Kline AP, Scott BJ, Meador LR, Srinivas D,
Martin-Garcia JM, Dörner K, Borges CR, Misra R, Hogue BG,
Fromme
P, Mor TS
PLoS One (2017) Feb 22;12(2):e0172529 (doi:
10.1371/journal.pone.0172529)
Structural
enzymology using X-ray free electron lasers
Kupitz C, Olmos JL Jr, Holl M, Tremblay L, Pande K, Pandey S,
Oberthür D, Hunter M, Liang M, Aquila A, Tenboer J, Calvey G,
Katz
A, Chen Y, Wiedorn MO, Knoska J, Meents A, Majriani V, Norwood T,
Poudyal I, Grant T, Miller MD, Xu W, Tolstikova A, Morgan A, Metz M,
Martin-Garcia JM, Zook JD, Roy-Chowdhury S, Coe J, Nagaratnam N, Meza
D, Fromme R, Basu S, Frank M, White T, Barty A, Bajt S, Yefanov O,
Chapman HN, Zatsepin N, Nelson G, Weierstall U, Spence J, Schwander P,
Pollack L, Fromme P, Ourmazd A, Phillips GN Jr, Schmidt M
Struct Dyn. (2016) Dec
15;4(4):044003 (doi: 10.1063/1.4972069)
The role of water molecules in the binding of
class I and II peptides to the SH3 domain of the Fyn tyrosine kinase
Camara-Artigas A, Ortiz-Salmeron E, Andujar-Sánchez M,
Bacarizo
J, Martin- Garcia JM
Acta Crystallogr F Struct Biol Commun. (2016) Sep;72(Pt 9):707-12 (doi:
10.1107/S2053230X16012310)
Characterization of Protein Nanocrystals Based on
the Reversibility of Crystallization
Dörner K, Martin-Garcia JM, Kupitz C, Gong Z, Mallet TC, Chen
L,
Wachter RM, Fromme P
Cryst Growth Des. (2016) Jul
6;16(7):3838-3845 (doi: 10.1021/acs.cgd.6b00384)
Serial
femtosecond crystallography: A revolution in structural biology
Martin-Garcia JM, Conrad CE, Coe J, Roy-Chowdhury S, Fromme P
Arch
Biochem Biophys. (2016) Jul 15; 602:32-47 (doi:
10.1016/j.abb.2016.03.036)
Biophysical Characterization of a Vaccine Candidate against HIV-1:
The Transmembrane and Membrane Proximal Domains of HIV-1 gp41 as a
Maltose Binding Protein Fusion
Gong Z, Martin-Garcia JM, Daskalova SM, Craciunescu FM, Song L,
Dörner K, Hansen DT, Yang JH, LaBaer J, Hogue BG, Mor TS,
Fromme
P
PLoS One (2015) Aug 21;10(8): e0136507 (doi: 10.1371/journal.pone.0136507)
Purification and biochemical characterization of the ATP synthase from
Heliobacterium modesticaldum
Yang JH, Sarrou I, Martin-Garcia JM, Zhang S, Redding KE, Fromme P
Protein Expr Purif. (2015) Oct; 114:1-8 (doi: 10.1016/j.pep.2015.05.006)
Electrostatic effects in
the folding of the SH3 domain of the c-Src tyrosine kinase:
pH-dependence in 3D-domain swapping and amyloid formation
Bacarizo J, Martinez-Rodriguez S, Martin-Garcia JM, Andujar-Sanchez M,
Ortiz-Salmeron E, Neira JL, Camara-Artigas A
PLoS One
(2014) Dec 9;9(12): e113224 (doi: 10.1371/journal.pone.0113224)
Purification
and biophysical characterization of the CapA membrane protein FTT0807
from Francisella tularensis
Martin-Garcia JM, Hansen DT, Zook J, Loskutov AV, Robida MD,
Craciunescu FM, Sykes KF, Wachter RM, Fromme P, Allen JP
Biochemistry (2014) Apr 1;53(12):1958-70 (doi: 10.1021/bi401644s)
3D
domain
swapping in a chimeric c-Src SH3 domain takes place through two hinge
loops
Cámara-Artigas A, Martínez-Rodríguez
S,
Ortiz-Salmerón E, Martín-García JM
J Struct Biol. (2014) Apr;186(1):195-203 (doi:
10.1016/j.jsb.2014.02.007)
Proliferating cell nuclear antigen (PCNA)
interactions in solution studied by NMR
De Biasio A, Campos-Olivas R, Sánchez R,
López-Alonso JP,
Pantoja-Uceda D, Merino N, Villate M, Martin-Garcia JM, Castillo F,
Luque I, Blanco FJ
PLoS One (2012) 7(11): e48390 (doi: 10.1371/journal.pone.0048390)
The
promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A
protein
Martin-Garcia JM, Luque I, Ruiz-Sanz J, Camara-Artigas A
Acta Crystallogr D Biol Crystallogr. (2012) Aug;68(Pt
8):1030-40 (doi: 10.1107/S0907444912019798)
pH-dependent
structural
conformations of B-phycoerythrin from Porphyridium cruentum
Camara-Artigas A, Bacarizo J, Andujar-Sanchez M, Ortiz-Salmeron E,
Mesa- Valle C, Cuadri C, Martin-Garcia JM, Martinez-Rodriguez S,
Mazzuca-Sobczuk T, Ibañez MJ, Allen JP
FEBS J.
(2012) Oct;279(19):3680-3691 (doi: 10.1111/j.1742-4658.2012.08730.x)
Interfacial water molecules in
SH3 interactions: a revised paradigm for polyproline recognition
Martin-Garcia JM, Ruiz-Sanz J, Luque I
Biochem J. (2012) Mar 1;442(2):443-51 (doi: 10.1042/BJ20111089)
High-resolution structure of an alpha-spectrin SH3-domain mutant with a
redesigned hydrophobic core
Cámara-Artigas A, Andújar-Sánchez M,
Ortiz-Salmerón E, Cuadri C, Cobos ES, Martin-Garcia JM
Acta Crystallogr Sect F Struct Biol Cryst
Commun. (2010) Sep 1;66(Pt 9):1023-7 (doi: 10.1107/S1744309110030095)
Intertwined dimeric structure for the SH3 domain
of the c-Src tyrosine kinase induced by polyethylene glycol binding
Cámara-Artigas A, Martín-García JM,
Morel B,
Ruiz-Sanz J, Luque I
FEBS Lett. (2009) Feb 18;583(4):749-53 (doi:
10.1016/j.febslet.2009.01.036)
Molecular basis of histone H3K4me3 recognition by ING4
Palacios A, Muñoz IG, Pantoja-Uceda D, Marcaida MJ, Torres
D,
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